NFL MATCHUP REPORT
December 22, 2025, 8:15 | Lucas Oil Stadium
San Francisco 49ers (10-4) VS Indianapolis Colts (8-6)
ODDS
|
|
|
|
|
|
|
| Moneyline |
|
|
211 |
210 |
|
| Spread |
|
|
6 -125 |
5.5 -110 |
|
| Total |
u |
u |
46 u -110 |
46.5 u -115 |
u |
RECENT FORM
POWER STATS
Yards Per Point
| Name | Offense | Defense | Differential |
| SF | 14.14 | 15.94 | -1.8 |
| IND | 12.77 | 15.84 | -3.07 |
Yards Per Pass
| Name | Offense | Defense | Differential |
| SF | 10.44 | 9.65 | 0.79 |
| IND | 10.76 | 10.44 | 0.32 |
Yards Per Rush
| Name | Offense | Defense | Differential |
| SF | 3.51 | 4.33 | -0.82 |
| IND | 4.84 | 3.74 | 1.1 |
SMART CHART
TEAM RECORDS
San Francisco 49ers
Indianapolis Colts
SUPERGRID
| Title | Stat | Rank | Stat | Rank |
| Away Team Overall Scoring vs Home Team Overall Defense | 24.57 | 11 | 21.64 | 12 |
| Away Team Road Passing vs Home Team Home Passing Defense | 238.00 | 8 | 210.71 | 17 |
| Away Team Road Rushing vs Home Team Home Rushing Defense | 91.25 | 27 | 107.29 | 13 |
| Home Team Overall Scoring vs Away Team Overall Defense | 28.00 | 6 | 20.93 | 11 |
| Home Team Home Passing vs Away Team Road Passing Defense | 234.43 | 11 | 252.75 | 28 |
| Home Team Home Rushing vs Away Team Road Rushing Defense | 163.14 | 1 | 104.38 | 8 |
HEAD TO HEAD SUMMARY
HEAD TO HEAD DETAIL
BETTING ODDS TRENDS
Indianapolis Colts
| Indianapolis is 2-4 ATS in its last 6 games |
| Indianapolis is 1-5 SU in its last 6 games |
| The total has gone UNDER in 4 of Indianapolis's last 6 games |
| Indianapolis is 8-1 SU in its last 9 games at home |
| The total has gone OVER in 17 of Indianapolis's last 25 games at home |
| Indianapolis is 4-1 ATS in its last 5 games when playing San Francisco |
| Indianapolis is 5-0 SU in its last 5 games when playing San Francisco |
San Francisco 49ers
| San Francisco is 5-1 ATS in its last 6 games |
| San Francisco is 5-1 SU in its last 6 games |
| The total has gone OVER in 4 of San Francisco's last 6 games |
| San Francisco is 6-2 ATS in its last 8 games on the road |
| San Francisco is 6-2 SU in its last 8 games on the road |
| The total has gone OVER in 5 of San Francisco's last 7 games on the road |
| San Francisco is 1-4 ATS in its last 5 games when playing Indianapolis |
| San Francisco is 0-5 SU in its last 5 games when playing Indianapolis |
