NFL MATCHUP REPORT
September 21, 2025, 4:25 | Levi's Stadium
Arizona Cardinals (2-0) VS San Francisco 49ers (2-0)
ODDS
|
|
|
|
|
|
Moneyline |
|
|
-130 |
-135 |
-123 |
Spread |
|
|
-1.5 -115 |
-2 -115 |
-1 -115 |
Total |
u |
u |
43.5 u -105 |
44.5 u -115 |
43.5 u 101 |
RECENT FORM
POWER STATS
Yards Per Point
Name | Offense | Defense | Differential |
ARI | 12.11 | 19.06 | -6.95 |
SF | 16.93 | 15.79 | 1.14 |
Yards Per Pass
Name | Offense | Defense | Differential |
ARI | 8.97 | 8.24 | 0.73 |
SF | 10.23 | 8.1 | 2.13 |
Yards Per Rush
Name | Offense | Defense | Differential |
ARI | 4.65 | 3.8 | 0.85 |
SF | 3.16 | 3.66 | -0.5 |
SMART CHART
TEAM RECORDS
Arizona Cardinals
San Francisco 49ers
SUPERGRID
Title | Stat | Rank | Stat | Rank |
Away Team Overall Scoring vs Home Team Overall Defense | 23.50 | 11 | 17.00 | 8 |
Away Team Road Passing vs Home Team Home Passing Defense | 130.00 | 24 | 0 | 0 |
Away Team Road Rushing vs Home Team Home Rushing Defense | 146.00 | 5 | 0 | 0 |
Home Team Overall Scoring vs Away Team Overall Defense | 21.50 | 19 | 17.50 | 10 |
Home Team Home Passing vs Away Team Road Passing Defense | 0 | 0 | 208.00 | 14 |
Home Team Home Rushing vs Away Team Road Rushing Defense | 0 | 0 | 107.00 | 15 |
HEAD TO HEAD SUMMARY
HEAD TO HEAD DETAIL
BETTING ODDS TRENDS
San Francisco 49ers
San Francisco is 3-8 ATS in its last 11 games |
San Francisco is 3-7 SU in its last 10 games |
The total has gone OVER in 4 of San Francisco's last 5 games |
San Francisco is 4-12 ATS in its last 16 games at home |
San Francisco is 17-8 SU in its last 25 games at home |
San Francisco is 2-5 SU in its last 7 games at home |
San Francisco is 4-2 ATS in its last 6 games when playing Arizona |
San Francisco is 5-9-1 ATS in its last 15 games when playing Arizona |
San Francisco is 4-2 SU in its last 6 games when playing Arizona |
The total has gone OVER in 6 of San Francisco's last 7 games when playing Arizona |
San Francisco is 2-6-1 ATS in its last 9 games when playing at home against Arizona |
San Francisco is 3-7 SU in its last 10 games when playing at home against Arizona |
The total has gone OVER in 5 of San Francisco's last 7 games when playing at home against Arizona |
Arizona Cardinals
Arizona is 9-4 ATS in its last 13 games |
Arizona is 4-2 SU in its last 6 games |
The total has gone OVER in 5 of Arizona's last 7 games |
Arizona is 7-3 ATS in its last 10 games on the road |
Arizona is 1-4 SU in its last 5 games on the road |
The total has gone UNDER in 4 of Arizona's last 5 games on the road |
Arizona is 2-4 ATS in its last 6 games when playing San Francisco |
Arizona is 2-4 SU in its last 6 games when playing San Francisco |
The total has gone OVER in 6 of Arizona's last 7 games when playing San Francisco |
Arizona is 6-2-1 ATS in its last 9 games when playing on the road against San Francisco |
Arizona is 7-3 SU in its last 10 games when playing on the road against San Francisco |
The total has gone OVER in 5 of Arizona's last 7 games when playing on the road against San Francisco |