<p>
On the season Michigan State ranks 72nd in the nation in total offense, and 12th in total defense and Indiana ranks 59th in total offense and 37th in total defense.
</p>
<h2>
Betting Line<br />
</h2>
<p>
Michigan State opened as the 4.5-point road favorite, and that line has not changed as of Tuesday morning while the total has slipped to 47.5 points after hitting the board at 48.
</p>
<p>
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</p>
<p>
<b>Last Games </b>
</p>
<p>
Michigan State suffered their first loss of the season against Arizona State losing 16-13, failing to cover the spread as a 4.5-point. The total points of 29 scored fell well below the 54 O/U line. Indiana moved to 3-0 with a 38-10 win over Ball State where they easily got the point spread cover as a 15-point favorite. The solid defensive play holding Ball State to just 10 points helped keep the total UNDER.
</p>
<h2>
Michigan State at Indiana NCAAF Betting Overview<br />
</h2>
<p>
Michigan State comes into this game still ranked, even after falling to Arizona State 16-13 where they gave it up late. They had 47 fewer total yards in the game (424 to 377), and they did not run the ball well averaging 2.3 yards per carry. In the 4th quarter, the Spartans were outscored 13-0.
</p>
<p>
MSU’s Brian Lewerke passed for 314 yards with a TD, and an INT in the loss to Arizona State and Cody White had 113 receiving yards. The Spartans rushed for only 63 yards in the game led by Conner Hayward, who had 22 yards on the ground.
</p>
<p>
The Spartans rushed for 165 yards in their season opener, and they have to establish the run in this game, and they will be facing an Indiana run defense that only ranks 94th in the nation and gave up over 200 rushing yards in their last game.
</p>
<p>
Indiana has won their first three games on the season, but they still open as home underdogs in this game. In their last game, they beat Ball State 38-10. The Hoosiers jumped out to a 24-3 halftime lead, and while they gave up over 200 rushing yards, they rushed for 255 yards.
</p>
<p>
The player that the Spartans have to contain is RB Stevie Scott (388 yards 3 TD), who rushed for 114 yards in the Ball State win and rushed for 204 yards in Indiana’s previous game.
</p>
<p>
<b>Head to Head:</b> last season at Indiana the Spartans beat the Hoosiers 17-9 in a defensive battle. Michigan State is 4-1 ATS in the previous five games facing Indiana.
</p>
<h2>
Sagarin Rankings<br />
</h2>
<p>
<b>Michigan State:</b> 82.55<br />
<b>Indiana:</b> 73.41
</p>
<p></p>
<h3>
Injuries<br />
</h3>
<p>
<b>MICHIGAN STATE </b>
</p>
<p>
[DE] 08/06/2018 - Dillon Alexander is out indefinitely ( Foot )<br />
[CB] 08/06/2018 - Josiah Scott is out indefinitely ( Undisclosed )<br />
[CB] 08/04/2018 - Tyson Smith is out for season ( Medical )<br />
[P] 09/11/2018 - Jake Hartbarger is OUT 6-8 weeks ( Undisclosed )<br />
[DT] 09/16/2018 - Mike Panasiuk is "?" Saturday vs. Indiana ( Undisclosed )<br />
[T] 09/16/2018 - Cole Chewins is "?" Saturday vs. Indiana ( Undisclosed )<br />
[LB] 09/16/2018 - Tyriq Thompson is "?" Saturday vs. Indiana ( Undisclosed )<br />
(!)[RB] 09/16/2018 - LJ Scott left last game, is "?" Saturday vs. Indiana ( Hamstring )<br />
[G] 09/17/2018 - David Beedle left last game, is "?" Saturday vs. Indiana ( Undisclosed )
</p>
<p>
<b>INDIANA </b>
</p>
<p>
[RB] 09/03/2018 - Cole Gest is out for season ( ACL )<br />
[RB] 08/24/2018 - Morgan Ellison is out indefinitely ( Suspension )<br />
[WR] 09/16/2018 - Jacolby Hewitt is "?" Saturday vs. Michigan State ( Undisclosed )<br />
[LB] 09/16/2018 - James Miller is "?" Saturday vs. Michigan State ( Undisclosed )<br />
[TE] 09/16/2018 - Ryan Watercutter is "?" Saturday vs. Michigan State ( Undisclosed )<br />
[TE] 09/16/2018 - TJ Ivy is "?" Saturday vs. Michigan State ( Undisclosed )<br />
[DL] 09/17/2018 - Gavin Everett is probable Saturday vs. Michigan State ( Undisclosed )<br />
[OL] 09/17/2018 - Mackenzie Nworah is downgraded to OUT Saturday vs. Michigan State ( Undisclosed )
</p>
<h2>
Key Betting Trends/Angles<br />
</h2>
<ul>
<li>
MSU is 2-8 ATS in their last ten road games
</li>
<li>
MSU is 6-2 ATS in their previous eight games after an ATS loss
</li>
<li>
MSU has an Under record of 5-2 in their last seven games after an ATS loss
</li>
<li>
IND is 2-9-1 ATS in their last 12 games
</li>
<li>
IND is 3-12-1 ATS in their previous 16 Big ten games
</li>
<li>
IND has an Over record of 13-3 in their last 16 games following a straight up win of more than 20 points
</li>
</ul>
<h2>
Head to Head Trends<br />
</h2>
<p>
The home team is 6-1 ATS in the last seven gamers between these teams.
</p>
<p>
Michigan State is 4-1 ATS in their last five games against Indiana.
</p>
<p>
In the last ten games between these teams, the Over record is 8-2.
</p>
<p>
In the last five games between these teams at Indiana, the Over record is 4-1.
</p>
<p>
<b>Next Game </b> Michigan State vs. Central Michigan<br />
Indiana @ Rutgers
</p>
<p></p>
<p>
<span style="font-size:16px;"><b><span style="color:#008000;">Get more details:</span></b> <a class="advblue" href="https://www.sportsbettingstats.com/ncaaf/matchup/975393"&gt; Michigan State at Indiana NCAAF Match-Up</a></span>
</p>