<p>Louisville needs one more win over its last two games to become bowl-eligible and hopes to get that win when it meets Duke for an ACC bout Thursday night in Durham. The Cardinals just snapped a two-game losing skid while the Blue Devils, following a promising start to this season, have lost six in a row. </p>
<p>Who do we like here, our free college football betting <a href="https://www.sportsbettingstats.com/ncaaf/free-ncaaf-picks&quot; title="Week 12 NCAA Football Picks">pick</a>?</p>
<h2>Louisville-Duke Betting Odds </h2>
<p>This week's college football betting lines opened the Cardinals as 19-point road favorites for this game, with an over/under of right around 60. Early betting action then edged that spread to 20 and the total to 60.5.</p>
<h2>Louisville Betting Preview </h2>
<p>The Cardinals are 5-5 on the season after beating Syracuse last Saturday 41-3. Louisville, coming off back-to-back tough losses to Clemson and North Carolina State, scored touchdowns on five of its first six possessions of the game, led 35-3 at the half, and cruised home from there for the easy victory and the cover as a three-point favorite.</p>
<p>The Cardinals out-gained the Orange 382-184.</p>
<p>So Louisville has now out-gained each of its last four opponents and out-rushed its last six foes.</p>
<p>Two weeks ago, the Cardinals led Clemson 24-17 in the fourth quarter but lost 30-24. Three weeks ago, they led NC State 10-7 in the fourth quarter but lost 28-13. In fact, Louisville either led or was tied in the fourth quarter in four of its five losses this season.</p>
<p>At 3-4 in conference play, the Cardinals are out of the running in the ACC, but at 5-5 overall, they need one more win over their last two games - they host Kentucky in the season finale next week - to return to a bowl, after missing out last season. </p>
<p> <section></p>
<ul>
<li>
<span style="font-size:16px;"><b><span style="color:#008000;">Get more details:</span></b> <a class="advblue" href="https://www.sportsbettingstats.com/ncaaf/matchup/1393891">Louisville at Duke 11/18/21 Betting Stats</a> </span>
</li>
</ul>
<p></section></p>
<h2>Duke Betting Preview </h2>
<p>Meanwhile, the Blue Devils are 3-7 on the season after losing at Virginia Tech last Saturday, 48-17. Duke gave up the first 14 points of the game and trailed 17-3 at the half. The Blue Devils then gave up the first 10 points of the second half to fall behind by 24 on their way toward defeat. </p>
<p>Duke also came up well short against the spread as a 14-point dog.</p>
<p>The Blue Devils got out-gained by the Hokies 573-343, gave up 297 yards on the ground, missed a make-able field goal when the game was still tied, and gave up a pick-6.</p>
<p>So Duke has now been out-gained and out-rushed by each of its last four opponents and by large margins.</p>
<p>Two games ago, the Dukies lost to Pitt 54-29; three games ago, they lost to Wake Forest 45-7; and four games ago, they lost to Virginia 48-0.</p>
<p>At 0-6 in conference play and 3-7 overall, Duke is playing out the string on its third straight bowl-less season.</p>
<p>These teams have met just once since Louisville joined the ACC back in 2014, a 24-14 Cardinals victory in 2016.</p>
<h2>College Football Betting Trends </h2>
<p>Duke is 15-10 ATS in its last 25 games as a home dog.</p>
<h2>Totals Report </h2>
<p>The Under is 7-3 in Cardinals games this season, which are averaging 55 total points.</p>
<p>Totals are split 5-5 in Blue Devils games this season, which are averaging 61 points.</p>